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This is an overabundance of cortisol hormone either from the pituitary gland of the adrenal glands.  These are usually a result of tumors in one of those two glands.  It can also be caused by steroid usage.  Because this is a disorder of the endocrine system, it is then spread throughout the body and can have a wide variety of symptoms, including the muscular system, the skeletal system, the dermis, the cardiovascular system, and central nervous system, the renal system, the liver, and the immune system.    This will affect dogs in middle age or older and should be considered very severe.  The progression of the disease will be very slow.  Symptoms can include:

  • Hair Loss
  • Black Head Pimples on the Abdomen
  • Increased Thirst
  • Increased Urination
  • Increased Hunger
  • Increased Panting
  • Abdomen Enlargement
  • Fatty Deposits on Neck and Shoulders
  • Lethargy
  • Muscle Weakness
  • Skeletal Brittleness
  • Shrinking of Testicles
  • Darkening of Skin
  • Thinning of the Skin
  • Bruising
  • Scaly Patches on the Skin
  • Behavioral Changes
  • Blood Clots
  • Hypertension
  • Diabetes
  • Heart Failure
  • Seizure
  • Death